which hormone suppresses spermatogenesis without affecting testosterone secretion?

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Male hypogonadism Symptoms & causes

Male hypogonadism Symptoms & causes

If you’re experiencing symptoms of low testosterone, such as a decrease in sex drive and hot flashes, talk to a healthcare provider. Conditions that affect how your hypothalamus and/or pituitary gland cause secondary hypogonadism. This is known as hypogonadotropic hypogonadism because there are low levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Those low levels cause decreased testosterone and sperm production. Having male hypogonadism can affect your self-image and, possibly, your relationships. Talk with your health care provider about how you can reduce the anxiety and stress that often accompany these conditions.

A pituitary tumor may need treatment with surgery, medicine, radiation or replacement of other hormones. Early detection in boys can help prevent problems from delayed puberty. Early diagnosis and treatment in men offer better protection against osteoporosis and other related conditions. Cleveland Clinic’s experts can help balance your hormones.

Any issue with your testicles, hypothalamus or pituitary gland can cause low testosterone (male hypogonadism). Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis. This treatment what is a basic metabolic panel lab test given only if the bones have matured enough. The U.S. Food and Drug Administration has approved one oral testosterone replacement, testosterone undecanoate (Jatenzo, Tlando, Kyzatrex). The lymph system absorbs it, so it might not cause the liver problems seen with other oral forms of testosterone.

LH then travels to your gonads (testicles or ovaries) and stimulates the production and release of testosterone. Your pituitary also releases follicle-stimulating hormone (FSH) to cause sperm production. Risks from testosterone therapy are most often due to doses that are too high. Many of these side effects go away when the dose is lowered.

LOH and low testosterone are more common in men who have Type 2 diabetes, overweight and/or obesity. Symptoms of low testosterone can vary considerably, particularly by age. Make a gift to our 2025 Drive to Cure Cancer and transform the way cancer is treated and defeated.

In one study, 30% of men who were overweight had low testosterone, compared to only 6% of those with weight in the normal range. In another study, 25% of men with Type 2 diabetes had low testosterone, compared to 13% of those without diabetes. Data suggest that about 2% of men may have low testosterone.

However, consistent hormone replacement therapy helps improve sex drive, ease symptoms of depression and increase energy levels for those experiencing low testosterone. Sometimes in primary hypogonadism testosterone levels are within the normal range and gonadotropins are high. Your specialist will help you understand if you need treatment, even with normal testosterone levels. Anyone taking testosterone replacement should have a medical checkup and blood tests several times during the first year of treatment and yearly after that. This is to see how well the treatment works and to watch for side effects.

Low testosterone (male hypogonadism) is a condition in which your testicles don’t produce enough testosterone. It has several possible causes, including conditions or injuries affecting your testicles, pituitary gland or hypothalamus. Another name for primary hypogonadism is hypergonadotropic hypogonadism. The high levels of these hormones would normally tell your testicles to produce more testosterone and sperm. However, if you have damaged (most commonly related to prior chemotherapy) or missing testicles, they can’t respond to the increased levels of gonadotropins. As a result, your testicles make too little or no testosterone and sperm.